Tabela de Sensibilidade a Antibióticos: Guia para Estudantes de Farmácia | Esquemas Farmacologia

ANTIBIOTIC(SENSITIVITY(CHART

Created'by'James'McCormack,'BSc(Pharm),'Pharm'D'and'Fawziah'Lalji,'BSc(Pharm),'PharmD,'FCSHP'

with'help'from'Michael'Legal'and'Tim'Lau'

Faculty'of'PharmaceuGcal'Sciences,'University'of'BriGsh'Columbia,'Vancouver,'BC

Bacteria'

Gram'PosiGve'Cocci

Gram'NegaGve'Bacilli

Gram'NegaGve'Coccobacilli

Anaerobes

Atypicals

Streptococci

Staphylococci

Streptococci'

(pneumoniae/'

pyogenes/'

viridans)

Enterococci'

(Group'D'strep)

Staph'

epidermidis'

(coagulase'

negaGve)

Staph'

aureus'

Methicillin'sensiGve

Community'

acquired'

Methicillin'

resistant

Hospital'

acquired'

Methicillin'

resistant

NonQbetaQlactamase'producing'

'Escherichia'coli,'

Klebsiella'pneumoniae,''

Haemophilus'inﬂuenzae'

BetaQlactamase'producing'

Escherichia'coli,'

Klebsiella'pneumoniae,'

Haemophilus'inﬂuenzae

SPACE'

'SerraGa'marcescens,'

Proteus'mirabilis,'

Acinetobacter'sp.,'

Citrobacter'sp.,'

Enterobacter'sp.

ESBL'

(Extended'spectrum'betaQ

lactamase'producing)'

Escherichia'coli,'

Klebsiella'pneumoniae'

Pseudomonas'

aeruginosa

Neisseria'meningiGdis

Neisseria'gonorrhea

Above'the'diaphragm'

(Peptostreptococcus)

Below'the'

diaphragm'

(Bacteroides'sp)

Clostridium'

diﬃcile

Mycoplasma'

pneumoniae,'

Chlamydophilia'

spp

Legionella'

pneumophilia

Chlamydia'

trachomaGs

LocaGon

Brain,'oral,'respiratory'tract,'

heart,'skin

Intraabdominal,'

urinary'tract

Skin,'prostheGcs'

Oral,'respiratory'tract,'heart,'skin,'bones/joint

Brain,'respiratory'tract,'intraabdominal,'urinary'tract

Brain

Pelvic'inﬂammatory'disease/STI

Oral,'respiratory'tract

Intraabdominal,'pelvic'

inﬂammatory'disease

Intraabdominal

Respiratory'tract

Pelvic'inﬂammatory'

disease/STI

Penicillins

Pencillin'V/G

Pencillin'GQIV

Pencillin'V/G

Amoxicillin/ampicillin

AmpicillinQIV

Amoxicillin/ampicillin

Cloxacillin

AmoxicillinQclavulanate

PiperacillinQtazobactam

Cephalosporins

Cefazolin/cephalexin

Cefuroxime

CefoxiGn/cefotetan

CeZriaxone/cefotaxime

Ceﬁxime

CeZazidime

Ceﬁpime

Ceﬁpime'

Carbapenems

Meropenem/imipenem

Ertapenem

Macrolides

Erythromycin

Clarithromycin/azithromycin

Clarithromycin/azithromycin'JUST'H.ﬂu

JUST'azithromycin

Clarithromycin/azithromycin

JUST'azithromycin

Tetracyclines

Tetracycline/doxycycline

Tetracycline/doxycycline''JUST'H.ﬂu

Tetracycline/doxycycline

Tigecycline

Fluoroquinolones'

Ciproﬂoxacin/norﬂoxacin'BUT'JUST'bladder'infecGons'for'norﬂoxacin

Ciproﬂoxacin

Levoﬂoxacin/moxiﬂoxacin

JUST'Moxiﬂoxacin

Levoﬂoxacin/moxiﬂoxacin

Aminoglycosides/polymyxin

Gentamicin/tobramycin/amikacin/colisGn

Lincosamides'

Clindamycin

GlycopepGdes/oxazolidinones

Vancomycin/linezolid/daptomycin'

Vancomycin/linezolid/'daptomycin'

Vancomycin'oral

TrimethoprimQSulfamethoxazole'

TrimethoprimQsulfamethoxazole

Chloramphenicol'

Metronidazole

Nitrofurantoin/fosfomycin'

(JUST'BLADDER'INFECTIONS)

Nitrofurantoin/fosfomycin'

JUST'E.faecalis

Nitrofurantoin/fosfomycin

Rifampin

Fidaxomicin

Cloxacillin)and)clindamycin)typically)have)less)than)40%)ac6vity)for)S.epidermidis,)thus)usage)depends)on)local)suscep6bility)data

Enterococci)has)two)main)species)A)Enterococcus)faecalis)and)Enterococcus)faecium)A)the)an6bio6cs)listed)work)well)for)E.faecalis,)but)have)limited)ac6vity)for)E.faecium)

Cephalosporins)have)inAvitro)ac6vity)for)SPACE)organisms)but)induce)produc6on)of)betaAlactamases))

Tigecycline)has)no)ac6vity)for)Pseudomonas)aeruginosa,)but)for)Acinetobacter)it)depends)on)local)suscep6bility)data;)Tigecycline)has)ac6vity)for)SPACE)organisms,)but)for)Proteus)spp)it)depends)on)local)suscep6bility)data

November'2015

Tabela de Sensibilidade a Antibióticos: Guia para Estudantes de Farmácia, Esquemas de Farmacologia

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ANTIBIOTIC SENSITIVITY CHART

Bacteria

Gram PosiGve Cocci Gram NegaGve Bacilli Gram NegaGve Coccobacilli Anaerobes Atypicals

Streptococci Staphylococci

Streptococci

(pneumoniae/

pyogenes/

viridans)

Enterococci

(Group D strep)

Staph

epidermidis

(coagulase

negaGve)

Staph

aureus

Methicillin sensiGve

Non-­‐beta-­‐lactamase producing

Escherichia coli,

Klebsiella pneumoniae,

Haemophilus influenzae

Beta-­‐lactamase producing

Escherichia coli,

Klebsiella pneumoniae,

Haemophilus influenzae

Pseudomonas

aeruginosa

Neisseria meningiGdis Neisseria gonorrhea

Above the diaphragm

(Peptostreptococcus)

Below the

diaphragm

(Bacteroides sp)

Clostridium

difficile

Mycoplasma

pneumoniae,

Chlamydophilia

spp

Legionella

pneumophilia

Chlamydia

trachomaGs

LocaGon

Skin, prostheGcs Oral, respiratory tract, heart, skin, bones/joint Brain, respiratory tract, intraabdominal, urinary tract Brain Pelvic inflammatory disease/STI Oral, respiratory tract

Penicillins

Cephalosporins

Carbapenems

Macrolides

Tetracyclines

Fluoroquinolones

Aminoglycosides/polymyxin Gentamicin/tobramycin/amikacin/colisGn

Lincosamides Clindamycin Clindamycin Clindamycin

GlycopepGdes/oxazolidinones Vancomycin/linezolid/daptomycin Vancomycin/linezolid/ daptomycin Vancomycin oral

Trimethoprim-­‐Sulfamethoxazole Trimethoprim-­‐sulfamethoxazole Trimethoprim-­‐sulfamethoxazole

Chloramphenicol Chloramphenicol Chloramphenicol Chloramphenicol

Metronidazole Metronidazole

Nitrofurantoin/fosfomycin

(JUST BLADDER INFECTIONS)

Rifampin Rifampin Rifampin

Fidaxomicin Fidaxomicin

November 2015

Non-‐beta-‐lactamase producing

Beta-‐lactamase producing

Trimethoprim-‐Sulfamethoxazole Trimethoprim-‐sulfamethoxazole Trimethoprim-‐sulfamethoxazole