Hematopoiesis (human) diagram, Notas de estudo de Biomedicina

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Multipotential hematopoietic (Hemocytoblast) stem cell +—DD—— Common myeloid | º Common lymphoid Stem cell Committed progenitor Mature cell Notes * Approximate scale information: 10 um * The morphological characteristics of the hematopoietic cells are shown as seen in a Wright's stain, May-Giemsa stain or May=Grinwald-Giemsa stain. Alternative names of certain cells are indicated between parentheses, * Certain cells may have more than one characteristic appearance. In these cases, more than one represenation of the same cell has been included. * Together, the monocyte and the lymphocytes comprise the agranulocytes, as opposed to the granulocytes (basophil, neutrophil and eosinophil) that are produced during granulopoiesis. * B., N. and E. stand for Basophilic, Neutrophilic and Eosinophilic, respectively. As in Basophilic promyelocyte. 1) The polychromatic erythrocyte (reticulocyte) at the right shows its characteristic appearance when stained with methylene blue or Azure B. 2) The erythrocyte at the right is a more accurate representation of what it looks like in reality when viewed through a microscope. 3) Other cells that arise from the monocyte: osteoclast, microglia (central nervous system), Langerhans cell (epidermis), Kupffer cell (liver). 4) For clarity, the T and B lymphocyte are split to better indicate that the plasma cell arises from the B-cell. Note that there is no difference in the appearance of B- and T-cells unless specific staining is applied. Myeloid dendritic cell > Plasma cell progenitor progenitor O Proerythroblast Lymphoblast Megakaryoblast (Pronormoblast) E e Basophilic erythroblast O. o E B. promyelocyte N. promyelocyte E. promyelocyte Monoblast Promegakaryocyte | | | | | Polychromatic erythroblast ; I o Prolymphocyte o B. myelocyte a E. myelocyte Promonocyte a | N. myelocyte | Orthochromatic erythroblast | (Normoblast) a o Ni) | B. metamyelocyte E. metamyelocyte [O N. metamyelocyte Megakaryocyte o =£ | | | Polychromatic erythrocyte » (Reticulocyte) 6) B. band Q a) E. band N. band Cd as oo & o Thrombocytes Erythrocyte ? ; i i Eosinophil ! TRrombossias à — Basophil Neutrophil ú | Monocyte I Natural killer cell romBopotésis Ervthropolesis Eranulopolesis (Large granular Iymphocyte) Monocytópoiesis Small Iymphocyte * | | o Jo | <>» r Te... B lymphocyte T Iymphocyte Mast cell Je ' | | | o. O (O) y Lymphopoiesis ) Macrophage Lymphoid dendritic cell > Aria Rad - 2007 (9)