MINIMUM INHIBITORY CONCENTRATION (MIC) AND MINIMUM
BACTERIOCIDAL CONCENTRATION (MBC) EXAMINATION IN PATAH
TULANG PLANT (EUPHORBIA TIRUCALLI) LATEX AGAINST CANDIDA
ALBICANS AND STAPHYLOCOCCUS AUREUS AS MOUTWASH
INGREDIENTS INNOVATION.
PENGUJIAN KADAR HAMBAT MINIMUM (KHM) DAN KADAR BUNUH
MINIMUM (KBM) PADA GETAH TANAMAN PATAH TULANG
(EUPHORBIA TIRUCALLI) TERHADAP BAKTERI CANDIDA ALBICANS
SERTA STAPHYLOCOCCUS AUREUS SEBAGAI INOVASI BAHAN OBAT
KUMUR
Ridhwana L, Kamalia N, Khairiah S.
Faculty of Dentistry, Lambung Mangkurat University
ABSTRACT
Patah tulang plant (Euphorbia tirucalli) are also called pencil plants, which
come from the euphorbiaceae family. E. tirucalli traditionally in Indonesia believed
have the advantage of being a constituent in pharmacology. The latex of E. tirucalli is
used as a traditional treatment which this plant is useful for treat gastrointestinal
epilepsy, asthma, impotency, injury, toothache, rheumatism, hemorrhoids, tumors and
cancer. E. tirucalli has antimicrobial activity which the latex is contain alkaloids,
tannins, steroids, flavonoids, triterpenoides, saponins and hydroquinone. Previous
studies have shown that E. tirucalli is effective in inhibiting microbial. As research
has been done by (Setyorini MS, et al. 2014) explained the E. tirucalli extract can
inhibit the growth of P. acnes in concentrations of 10% and C. albicans in
concentration of 6%. However, there has been no studies explaining the MIC and
MBC in S. Aureus. This is the reason of our study which is to test E. Tirucalli
effectiveness to kill or inhibit S. Aureus growth. The MIC measurement will be
carried out by Kirby Bauer method on a blank disc dipped in Euphorbia tirucalli
latex, while the MBC measurement uses a liquid dilution and solid dilution method.
Extract will be made at the Mathematics and Natural Sciences Laboratory of the
Lambung Mangkurat University at the MIPA Faculty in Banjarbaru so that the extract
of E. tirucalli latex will be studied to become a mouthwash ingredients product that
can improve oral health as anti microbial.
ABSTRAK
Tanaman patah tulang (Euphorbia tirucalli) disebut juga tanaman pensil, yang
berasal dari family euphorbiaceae. E. tirucalli Secara tradisional dipercaya memiliki
keuntungan sebagai konstituen dalam farmakologi. Getah dalam E. tirucalli
digunakan sebagai pengobatan secara adat istiadat yang mana tanaman ini berguna
