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TAMU BIOL 319 Test 2 COHN Questions with Verified Solutions, Exams of Advanced Education

TAMU BIOL 319 Test 2 COHN Questions with Verified Solutions

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2024/2025

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TAMU BIOL 319 Test 2 COHN Questions
with Verified Solutions
"Bruised bones" is damage to which structure(s)? - ANS-Periosteum
A lateral blow to the knee will tear which structures? - ANS-- ACL
- Meniscus
- TCL
According to Wolff's law, bone changes are caused by what type of cell? - ANS-
Osteoblasts
At what age does the fetal skeleton begin to ossify? - ANS-8-12 weeks
Biaxial joints allow for ________. - ANS-Circumduction
Define: Ankylosis - ANS-Fusion of joints due to rheumatoid arthritis
Define: Anulus fibrosis - ANS-Ring of fibrocartilage around vertebral disks
Define: Apositional growth - ANS-Bone thickening
Define: Bursa - ANS-Flat sacks of synovial fluid that act as ball bearings between a joint
capsule and bone
Define: Cartilaginous joint - ANS-Joints that DO have cartilage, but lack a joint cavity
Define: circumferential lamellae - ANS-Lamellae that are the outermost lamellae and
are in contact with the periosteum
Define: Diapedesis - ANS-Leaky capillaries give macrophages a medium to collect and
travel in
Define: Haversion canal - ANS-Conduits between lacunae that allow for one nerve, one
artery, and one vein.
Define: Hyperplasia - ANS-Mitotic growth of tissue
Define: Labrum - ANS-Fibrocartilage in glenoid cavity that allows for head of humerus
insertion
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TAMU BIOL 319 Test 2 COHN Questions

with Verified Solutions

"Bruised bones" is damage to which structure(s)? - ANS-Periosteum A lateral blow to the knee will tear which structures? - ANS-- ACL

  • Meniscus
  • TCL According to Wolff's law, bone changes are caused by what type of cell? - ANS- Osteoblasts At what age does the fetal skeleton begin to ossify? - ANS-8-12 weeks Biaxial joints allow for ________. - ANS-Circumduction Define: Ankylosis - ANS-Fusion of joints due to rheumatoid arthritis Define: Anulus fibrosis - ANS-Ring of fibrocartilage around vertebral disks Define: Apositional growth - ANS-Bone thickening Define: Bursa - ANS-Flat sacks of synovial fluid that act as ball bearings between a joint capsule and bone Define: Cartilaginous joint - ANS-Joints that DO have cartilage, but lack a joint cavity Define: circumferential lamellae - ANS-Lamellae that are the outermost lamellae and are in contact with the periosteum Define: Diapedesis - ANS-Leaky capillaries give macrophages a medium to collect and travel in Define: Haversion canal - ANS-Conduits between lacunae that allow for one nerve, one artery, and one vein. Define: Hyperplasia - ANS-Mitotic growth of tissue Define: Labrum - ANS-Fibrocartilage in glenoid cavity that allows for head of humerus insertion

Define: Luxation - ANS-Dislocation Define: Medullary Cavity - ANS-Space within bones that holds marrow Define: Neural pulposis - ANS-Inner portion of vertebral disk Define: Osteoarthritis - ANS-Degradation of hyaline cartilage with age Define: Osteoblasts - ANS-- Come from osteoprogenitor cells

  • Secrete collagen and organic matrix to thicken bone
  • Give rise to osteocytes Define: Osteoclast - ANS-- From bone marrow
  • Multinuclated
  • Destroy bone by secreting HCl
  • Destroys collagen/organic matrix by secreting enzymes Define: Osteocyte - ANS-- Former osteoblast
  • Maintains bone in its immediate vicinity Define: Osteoid - ANS-- Non mineralized, organic portion of bone
  • Located in bone matrix Define: Osteophyte - ANS-Bone spurs caused by bone rubbing on bone Define: Osteoprogenitor cells - ANS-- Bone stem cells
  • Come from periosteum
  • Give way to osteoblasts Define: Pannus - ANS-The thickening and scarring of synovial membranes due to rheumatoid arthritis Define: Periosteum - ANS-Dense connective tissue covering all living bones Define: Rheumatoid arthritis - ANS-Autoimmune disease in which synovial membranes are attacked Define: Rotator cuff - ANS-band of tendon that wraps around lateral side of humerus to pull it tightly into the glenoid cavity Define: Syndesmoses - ANS-Bones connected by short ligaments of dense CT Define: Tendon sheath - ANS-Bursa-like structure in shoulder joint that wraps around biceps brachii; reduces friction and wear on tendon

Epiphyseal plates are an example of what type of joint? - ANS-Cartilaginous What is the basic structure of GH? - ANS-Two molecules of tyrosine bound together by a molecule of iodine What is the basic, functional issue of osteoporosis? - ANS-Too many osteoclasts and not enough osteoblasts What is the consistency of ground substance? - ANS-Syrupy What is the formal name for beams and struts wrt bone? - ANS-Trabeculae What is the function of hydroxyapetite in bone? - ANS-- Make bones hard and rigid

  • Infuse with extracellular matrix What is the function of thyroid hormone? - ANS-- Stimulate growth in all tissues INDIRECTLY by helping big player hormones reach full effect
  • Brain dev. in infants What is the GH/IGF1 mechanism? - ANS-GH acts on liver to release IGF1 which stimulates growth plates What is the major function of yellow marrow? - ANS-Fat reserves What is the net result of chondrocytes in the epiphyseal plate undergoing calcification? - ANS-Provide material to build new bone for lengthening long bones What is the osteoclast inhibitor used for osteoporosis treatment? - ANS-Bis- phosphorate What makes up the inorganic matrix of bone? - ANS-Hydroxyapetite What organ produces calcitonin? - ANS-Thyroid What secretes synovial fluid? - ANS-Synovial membrane Ground substance of bone is comprised of __________. - ANS-Protoglycans, glycoproteins, and water Growth occurs in what direction at the epiphyseal plate? - ANS-From epiphysis to diaphysis How do chondrocytes in the epiphyseal plate undergo apoptosis? - ANS-Calcification

How do osteoclast inhibitors work? - ANS-Encourage osteoclast apoptosis How does articular cartilage within a synovial joint receive nutrients - ANS-From nutrients in the synovial fluid How does dentin compare to true bone? - ANS-- Squishier

  • Nonvascularized, no trabeculae, lacks innervation
  • Produced by dentinocytes How does estrogen influence the growth plate throughout a female's life? - ANS-Initially it stimulates quick growth, but between 16 and 18 degrades the growth plate How does parathyroid hormone interact with the kidney? - ANS-- Causes kidneys to not excrete as much calcium in urine
  • Cause kidney to excrete hormone that boosts vitamin D synthesis How does testosterone influence the growth plate throughout a male's life? - ANS- Initially causes VERY fast growth and then, later than for females, degrades the growth plate How many amino acids is GH made of? - ANS-About 200 Hydroxyapetite is made of ___________. - ANS-Calcium phosphate crystal Hypercalcemia causes and effects? - ANS-- Too high calcium levels in blood
  • Apathy, sleep, coma Hypocalcemia causes and effects? - ANS-- Too low calcium levels in blood
  • Convulsions In older adulthood, what is the effect of less sex hormones on bones? - ANS-Causes osteoclast activity to be favored In the womb, the early skeletal system comes from __________. - ANS-Embryonic mesenchyme In what bones is red marrow replaced by yellow marrow? - ANS-Long bones In which direction(s) is the shoulder joint least stable? - ANS-Posterior, Inferior, anterior Joint capsules are _______ sealed. - ANS-Hermetically Multiaxial joints allow for ______ and _________. - ANS-Circumduction and long axis rotation

Trabeculae are filled with _________. - ANS-Marrow What are SERMs? - ANS-Selective estrogen receptor moderator; selectively fiddle with estrogen receptors What are the basics to Wolff's law? - ANS-Stresses on bone lead to remodeling along stress lines/areas What are the extracapsulary ligaments of the knee joint? - ANS-Tibial and Fibular collateral ligaments What are the extracellular fibers of bone matrix comprised of? - ANS-Collagen What are the four major stages to bone healing? - ANS-- Hematoma formation

  • Callus formation
  • Callus ossification
  • Bone remodeling What are the intracapsulary ligaments of the knee joint? - ANS-ACL and PCL What are the other names for spongy bone? - ANS-- Trabecular bone
  • Cancellous bone What are the proximal causes that effect bone growth? - ANS-Nutrition and hormones What are the spider web lookin bits within lacunae called and what is it's function? - ANS-Cannaliculi; Allows vasculature to osteocytes and allows them to connect to one another What are the symptoms of vitamin C deficiency (scurvy)? - ANS-Bloody gums and collapsing connective tissue What are the three theories on how bone knows how to grow in stress areas? - ANS-- Stress on crystals cause slight electric current
  • Fluid differences in bone
  • Paracrine activity What are the three types of joints (wrt movablity)? - ANS-- Synarthrotic
  • Amphiarthrotic
  • Diarthrotic What are the three ways calcitonin works in the body? - ANS-- Cause kidneys to filter out more calcium
  • Decrease osteoclast activity
  • Less vitamin D production

What are the three ways the body responds to hypocalcemia using PTH? - ANS-- Synthesize vitamin D

  • Promote osteoclast activity
  • Retain calcium in kidneys What are the two layers of the periosteum and what are made of? - ANS-Two layers:
  • Inner: Cambian layer, osteoprogenitor cells
  • Outer: Fibrous layer, dense irregular tissue and fibroblasts What are the two major functions of ligaments? - ANS-- Connect bone to bone
  • Hold organs together What can cause bursitis? - ANS-Overuse or bacterial infection What causes gout? - ANS-Too much uric acid in joints that lead to uric acid crystal formation What cell is primarily responsible for releasing Ca^2+ and PO4^3- into the blood? - ANS-Osteoclast What comprises compact bone? - ANS-Osteons What comprises diploë? - ANS-Spongy bone and red bone marrow What does PTH do to bone cells? - ANS-Causes osteoclast activity to increase What does red marrow produce? - ANS-Red blood cells What drug is used to treat gout? - ANS-Colchicine What effect do stress hormones have on bone? - ANS-Stunt their growth What factor is primarily responsible for bone growth? - ANS-Genetics What factors exasterbate osteoporosis? - ANS-- Less physical activity
  • Less calcium intake
  • Vitamin D activity
  • Decreased blood flow What foods exasterbate gout? - ANS-Sardines and organ meats What hormone affects the rate of closure of the epiphyseal plate? - ANS-Sex hormone What is a sessamoid bone? - ANS-A bone that grows with and within a tendon

What type of hormone is vitamin D? - ANS-Modified steroid (cholesterol) What type of immune cells are involved in rheumatoid arthritis? - ANS-- Dendritic

  • Neutrophils
  • T cells
  • B cells What's another name for a haversion canal? - ANS-Central canal What's the difference between a prolapsed disk and a herniated one? - ANS-Prolapsed = slipped Herniated disk = rupture What's the main difference between acromegaly and gigantism? - ANS-Pituitary tumor occuring before (gigantism) or after (acromegaly) growth plate sealing When the sutures completely fuse what are they called? - ANS-Synastoses Where are gomphotic joints located? - ANS-Jaw and teeth Where are suture joints found? - ANS-Skull only Where do osteoclasts collect? - ANS-Periosteum and endosteum Where do osteoclasts come from? - ANS-Bone marrow: when blood cells fuse osteoclasts result Where is long bone growth most highly concentrated? - ANS-Epiphyseal plate Where is parathyroid hormone secreted? - ANS-Directly into blood Where is spongy bone concentrated? - ANS-Upper portion of the diaphysis Which intracapsulary ligment is connected to the meniscus? - ANS-ACL Why is the PCL least likely to tear in a lateral injury? - ANS-It's thicker Within a synovial joint, what caps the end of the bones? - ANS-Articular cartilage Within bone, how are trabeculae arranged? - ANS-Along stress lines Within the pubic symphysis, what is the arrangement of hyaline and fibrocartilage? - ANS-Fibrocartilage sandwiched between hyaline sandwiched between bone