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Life Cycle and Clinical Features of Cestodes, Summaries of Parasitology

An in-depth analysis of the life cycle, clinical features, and lab diagnosis of various cestodes, including diphyllobothrium latum, taenia saginata, taenia solium, and hymenolepis nana. It covers the different larval stages, the structure of the adult worm, and the symptoms associated with each type of cestode infection. The document also discusses the lab diagnosis and treatment options for each infection.

Typology: Summaries

2022/2023

Available from 06/12/2024

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elisha-sarcena 🇵🇭

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CESTODES
EGG
LARVA
ADULT WORM
LIFE CYCLE
INFECTIVE
FORM:
CLINICAL FEATURES
LAB DIAGNOSIS:
Pseudophyllidean:
Diphyllobothrium
latum
(fish tapeworm)
(broad tapeworm)
• operculated, has
knob on other end
• passed as
unembryonated
egg
3 larval stages:
L1 = coracidium
(ciliated)
L2 = procercoid
L3 = plerocercoid
(encysted)
• Scolex = spoon
shaped, with 2-
slit longitudinal
groove (bothria)
• Strobila =
bilobed ovary,
rosette-like
uterus,
3 Hosts:
Diphyllobothriasis
• cause mechanical
obstruction
• cause pernicious
anemia
(bothriocephalus
anemia)
• cause megaloblastic
anemia
These anemia is
caused by vit. B12
deficiency.
Stool microscopy:
Detection of
eggs/proglottids
Serodiagnosis:
coproantigen
DH = Man
Plerocercoid
larva
IH #1 = Copepods,
crustaceans
Coracidium
IH #2 = Freshwater
fish
Procercoid
larva
Spirometra spp.
Same as D. latum
Same as D. latum:
Only that its name of
plerocercoid larva
(L3) = SPARGANUM
Same as D.
latum
Same as D. latum
with 3 hosts:
Same as D. latum
Sparganosis
-caused by ectopic
infection of sparganum.
-sparganum penetrates
subcutaneous tissue,
forming nodules.
Diagnosis only possible
after surgical removal of
nodules
•definitive treatment is
surgical removal of
nodules
DH= dog, cat
IH#1 = copepods,
cyclops
IH#2 = snakes, frogs,
fishes
man is accidental
host and dead end
Cyclophyllidean
Taenia saginata
(Beef tapeworm)
Embryonated egg,
striated
embryophore
Cysticercus bovis
•Scolex=
rostellum and
hooks ABSENT
• Longer than T.
solium
Has (1) genital
pore/ vaginal
sphincter
2 HOSTS:
DH= Man
IH = Cow/cattle
Cysticercus bovis
Intestinal taeniasis
Stool microscopy:
Demonstration of
eggs/proglottids/scolex
Coproantigen
Taenia solium
(Pork tapeworm)
Embryonated egg,
striated
embryophore
Cysticercus
cellulosae
•Scolex =
rostellum and
hooks PRESENT
• Shorter than T.
saginata
2 HOSTS:
DH= Man
IH = Pigs
Cysticercus
cellulosae
& embryonated
egg (for
cysticercosis)
Intestinal taeniasis
and
Cysticercosis
For intestinal taeniasis:
• Stool microscopy:
demonstration of
eggs/proglottids/scolex
For cysticercosis:
• Biopsy = definitive method
pf3

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CESTODES EGG LARVA ADULT WORM LIFE CYCLE INFECTIVE

FORM:

CLINICAL FEATURES LAB DIAGNOSIS: Key takeaways: Pseudophyllidean : Diphyllobothrium latum (fish tapeworm) (broad tapeworm)

  • operculated, has knob on other end
    • passed as unembryonated egg 3 larval stages: L1 = coracidium (ciliated) L2 = procercoid L3 = plerocercoid (encysted)
  • Scolex = spoon shaped, with 2 - slit longitudinal groove (bothria)
  • Strobila = bilobed ovary, rosette-like uterus , 3 Hosts: Diphyllobothriasis
  • cause mechanical obstruction
  • cause pernicious anemia (bothriocephalus anemia)
  • cause megaloblastic anemia These anemia is caused by vit. B deficiency. Stool microscopy: Detection of eggs/proglottids Serodiagnosis: coproantigen Common name: Fish tapeworm
  • longest, broad, and largest tapeworm infecting humans
  • embryogenesis & hatching to L happens in the environment
  • feeds on Vit. B
  • has paratenic life cycle DH = ManPlerocercoid larva IH #1 = Copepods, crustaceans ➔ Coracidium IH #2 = Freshwater fish ➔ Procercoid larva Spirometra spp. Same as D. latum Same as D. latum : Only that its name of plerocercoid larva (L3) = SPARGANUM Same as D. latum Same as D. latum with 3 hosts: Same as D. latum Sparganosis
  • caused by ectopic infection of sparganum.
  • sparganum penetrates subcutaneous tissue, forming nodules. Diagnosis only possible after surgical removal of nodules
  • definitive treatment is surgical removal of nodules
  • once the sparganum invades the subcutaneous tissue and form nodules, it will no longer develop into adult worm DH= dog, cat IH#1 = copepods, cyclops IH#2 = snakes, frogs, fishes
  • man is accidental host and dead end Cyclophyllidean Taenia saginata (Beef tapeworm) Embryonated egg, striated embryophore Cysticercus bovis •Scolex= rostellum and hooks ABSENT
  • Longer than T. solium
  • Has (1) genital pore/ vaginal sphincter

2 HOSTS:

DH= Man IH = Cow/cattle Cysticercus bovis Intestinal taeniasis Stool microscopy: Demonstration of eggs/proglottids/scolex Coproantigen Definitive diagnosis of unarmed scolex Taenia solium (Pork tapeworm) Embryonated egg, striated embryophore Cysticercus cellulosae •Scolex = rostellum and hooks PRESENT

  • Shorter than T. saginata

2 HOSTS:

DH= Man IH = Pigs Cysticercus cellulosae & embryonated egg (for cysticercosis) Intestinal taeniasis and Cysticercosis For intestinal taeniasis:

  • Stool microscopy: demonstration of eggs/proglottids/scolex For cysticercosis:
  • Biopsy = definitive method Treatment for intestinal taeniasis: praziquantel For cysticercosis : excision is the best method

Taenia saginata asiatica -- Cysticercus Located primarily in LIVER (not muscle)

- 2 HOSTS:

DH= Man IH = PIG

      • • closely related to T. saginata - morphologically similar except SMALLER Multiceps multiceps (Taenia multiceps)
  • Coenurus (spherical/ovoid bladder worm) Has multi invaginated protoscolices

2 HOSTS:

DH = Dog,wolf, fox IH = Sheep, cattle man is accidental intermediate host Coenurus Coenurosis •Main site in sheep= CNS •Main site in human= brain and subcutaneous tissue •Surgical removal, only mode of treatment Echinococcus granulosus (Dog tapeworm) (smallest & shortest tapeworm of medical importance) Indistinguishable from Taenia spp. Hydatid cyst (remains invaginated within vesicular body) (in DH, it exvaginate and develop)

  • hydatid cyst is very dangerous because once it breaks, the patient could suffer from anaphylactic shock or death. •the cyst contains HYDATID FLUID which is very toxic and very antigenic Small
  • scolex, short neck, short strobila Strobila has only 3 proglottids

1 immature 1 mature 1 gravid

2 HOSTS:

DH= Dog(optimal), wolf, fox IH = Sheep(ideal) and cattle Man is accidental intermediate host Embryonated eggs Hydatid Echinococcosis Hepatomegaly ( LIVER = 1st filter organ) Cough, pneumothorax, dyspnea ( LUNG = 2nd filter organ) Hematuria ( KIDNEY = 3rd filter organ) Other sites: brain, spleen, bones, pelvic organs (4TH^ filter organs) •Imaging techniques

  • Casoni’s intradermal test

hypersensitivity skin test positive = wheal and flare or swelling and redness •The hydatid cyst consists of three layers to protect it from breaking easily. Pericyst Ectocyst Endocyst - The cyst also has mother/brood capsule where the cyst can still produce more cysts. Echinococcus multilocularis (rare but serious) - - Smaller than E. granulosus Has same life cycle as E. granulosus DH= dog,cat,fox IH= rodents MOT = ingestion of fruits and vegies contaminated with eggs Embryonated eggs Alveolar Echinococcosis or Alveolar Multilocular Hydatid

  • •found in the liver •termed as “alveolar” because it mimics the alveoli of the lungs
  • has the capacity to spread