Summary of Metabolic Pathways, Exercises of Biochemistry

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Summary of Metabolic Pathways of Glucose

BCHEM-C

Submitted by:

Shaira Mariz L. Seva

BSN 1 - C

A) Using a tabulated format, indicate the starting molecule for each step of the

pathway, the molecules involved in the process and the number of ATPs

produced during each cellular respiration process:

Starting

Molecule(s)

Identify the molecules

involved for each step in

the process

List down the

enzymes involved in

the process

Number of

ATP(s)

Produced

Glycolysis Glucose

1 St^ Phase Step 1: Glucose, Glucose 6- phosphate, ATP Step 2: Glucose 6-phosphate, Fructose 6-Phosphate Step 3: Fructose 6-Phosphate , Fructose-1,6-biphosphate, ATP Step 4: Fructose, Dihydroxyacetone phosphate (DHAP), Glyceraldehyde- 3 - phosphate 2 nd^ Phase Step 5: Dihydroxyacetone phosphate (DHAP), Glyceraldehyde 3 - phosphate Step 6: Glyceraldehyde 3 - phosphate, 1,3-Biphosphoglycerate, NAD+, NADH, H+, PO 4 Step 1: Hexokinase Step 2: Phosphoglucose isomerase Step 3: Phosphofructokinase- 1 Step 4: Aldolase Step 5: Triosephosphate isomerase Step 6: Glyceraldehyde 3 - phosphate dehydrogenase Step 7: Phosphoglycerate kinase Step 8: Phosphoglyceromutase Step 9: Enolase Step 10: Pyruvate kinase

2 ATP

Step 8: Oxaloacetate, Malate, NAD+, NADH Succinate Dehydrogenase, Fumarase, Step 8: Malate Dehydrogenase

ETC

NADH and

FADH 2

Complex I: NADH Dehydrogease Complex NADH, NAD+, ubiquinone (Q), ubiquinol (QH 2 ), FMN, FE-S Q and Complex II: Succinate Dehydrogenase Complex Hydrogen, Fumarate, FADH 2 , ubiquinone (Q), ubiquinol (QH 2 ) Complex III: Cytochrome Reductase QH2, Cytochrome A, B, C Complex IV: Cytochrome C Oxidase, Cytochrome C, O 2 , H 2 NADH-coenzyme Q oxidoreductase, Succinate-Q oxidoreductase, Q cytochrome c oxidoreductase, Cytochrome C oxidase ATP Synthase NADH dehydrogenase, Formate dehydrogenase

Total number of ATPs produced from one glucose molecule: 36 - 38 ATP’s

B) Obtain a LABORATORY RESULT from your parents, siblings or any relative

that underwent a laboratory procedure (Urine Analysis).

Examine the CLINICAL CHEMISTRY and tabulate the result:

CLINICAL CHEMISTRY

Conventional Units S.I. Units

Analyte Result Normal Range Result Normal Range

Random Blood

Sugar

113 .48 mg/dL

mg/dL

4 .382 mmol/L

mmol/L

Diagnosis/ Interpretation of Result:

The patient’s RBS is 113.48 mg/dL which is within the

normal range. Therefore, the patient is normal.