Structure-Functions Biomolecules - Midterm Exam Solutions | BIS 102, Exams of Biology

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lof3 BIS 102 Name Kom Fall, 2012 Last 7 First K. Hilt Second Midterm Score (100): Equations: pH = pK, + log {[b}/[a]} AG = AH - TAS pK,’s of amino acid side chains: D (3.9), E (4.2), H (6.0), C (8.3), Y (10.1), K (10.5), R (12.5) pK, of amino acid a-COOH (2.1); pK, of amino acid a-NH;° (9.6) pK, of oligopeptide N-terminus (7.4); pK, of oligopeptide C-terminus (3.6) 1, (8 pts.) The weak bond that plays the predominant role in protein folding is droglobic The weak bond that plays the most important role in communication in hemoglobin is_/ort<. base. The weak bond that plays the predominant role in stabilizing a B-pleated sheet is hydrogen bonde. . The weak bond that occurs when C=O and N-H groups of peptide bonds come together a¥ part of 2° and 3° structure is hydeegan banda. - Fill in the above blanks with one or more words). 2. (8 pts.) How many moles of O will be released if a liter of blood containing 54 g of hemoglobin is transferred from 60 torr, pH 7.6 to 15 torr, pH 7.2? Hemoglobin has a molecular Weight of 68,000. Show all calculations ahd reasoning" 1% - 15% = 5%, S44 = 74H & ee ee 8 —e— 02 binding to Hb at pH 7.6 0. O binding to Hb at pH 7.2 % Oo Bound 888 $B eB B 6 0 10 20 30 0 30 60 wm pO2 (tor) ~4 (TAA 1D wk HEH Oo /ab) = 3,176 * D> mal 0, band -3 (3:\%* (0 wot 22 \(o. #5) = 2.044 x 1D 3 el oy released © 2.7 x 107 rk Oo,