Second Midterm Answers - Structure and Function of Biomolecules | BIS 102, Exams of Biology

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lof4 BIS 102 Name Keun Fall, 2011 Last 7 First K. Hilt Second Midterm Score (100): Equations: pH = pK, + log {[b}/{a]} AG = AH - TAS pK,’s of amino acid side chains: —_D (3.9), E (4.2), H (6.0), C (8.3), Y (10.1), K (10.5), R (12.5) pK, of amino acid a.-COOH (2.1); pK, of amino acid a-NH;* (9.6) pK, of oligopeptide N-terminus (7.4); pK, of oligopeptide C-terminus (3.6) pK, of NH," (9.25) 1, (5 pts.) Antibodies have several disulfide bonds. These tetramers are secreted into the blood. The disulfide bonds would be considered to be part of (circle the letter of the best answer): a) 1° and 2° structure b) 2° and 3° structure S. / ¢) 1° and 3° structure \e 37? * Ca) 1° and 4° structure e) 3° and 4° structure 2. (15 pts.) There are three important histidine residues in Hb. Identify them; rank them, and explain what each one does. If they do more than one thing, then list them all. Limit your answers to the lines provided. #1 in importance Name: _frovimal Function(s): .) (inka movement 4, Fel 40 movement of. solr widen, 2) gorects beck. side of Fer? Evom toactiney with Lo #2 in importance Name: Distal Function(s): 1. 1 Stavenner 2. makes H-berd to OD 3. fovcen CO +o bid ot an asseh Ge, #3 in importance Name: C-terminal Y of P-subunits Function(s): |. cayvied waste HS Prom +iesues 2, telgs Ad load 0, to bssuen ly creating +1- ond with De re