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Introduction to Cell Biology: The Building Blocks of Life, Study notes of Human Genetics

This lecture delves into the fascinating world of cells, exploring their structure, function, and significance as the basic unit of life. It covers the discovery of cells, the two main types (prokaryotic and eukaryotic), and the various organelles within eukaryotic cells and their functions. The document also discusses why cells are called the building blocks of life and the diversity of cells, highlighting examples of different cell types and their specialized functions.

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2015/2016

Available from 04/26/2024

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Introduction to Cell Biology
I. Introduction
Living things come in all shapes and sizes, from the tiniest bacteria to
the giant blue whale. But what's the most basic unit that all living
things share? That's right, the cell! Cells are like tiny factories,
carrying out all the essential functions that define life.
In this lecture, we'll dive into the fascinating world of cells, exploring
their structure, function, and why they're called the building blocks of
life.
II. The Discovery of Cells
Believe it or not, cells are too small to see with the naked eye. It
wasn't until the invention of the microscope in the 17th century that
scientists could observe these tiny marvels.
โ—Robert Hooke (1665): He observed cork, a dead plant tissue,
and saw tiny box-like compartments. He called them "cells," after
the small rooms monks lived in. These were cell walls, but they
gave the first glimpse into the cellular structure.
โ—Anton van Leeuwenhoek (1674): He observed pond water and
discovered single-celled organisms, which he called
"animalcules." These were the first observations of living cells.
III. The Basic Unit of Life
There are two main types of cells:
โ—Prokaryotic Cells: Simpler, lack a membrane-bound nucleus
and other complex organelles. Their genetic material (DNA) is
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Introduction to Cell Biology

I. Introduction

Living things come in all shapes and sizes, from the tiniest bacteria to the giant blue whale. But what's the most basic unit that all living things share? That's right, the cell! Cells are like tiny factories, carrying out all the essential functions that define life. In this lecture, we'll dive into the fascinating world of cells, exploring their structure, function, and why they're called the building blocks of life.

II. The Discovery of Cells

Believe it or not, cells are too small to see with the naked eye. It wasn't until the invention of the microscope in the 17th century that scientists could observe these tiny marvels. โ— Robert Hooke (1665): He observed cork, a dead plant tissue, and saw tiny box-like compartments. He called them "cells," after the small rooms monks lived in. These were cell walls, but they gave the first glimpse into the cellular structure. โ— Anton van Leeuwenhoek (1674): He observed pond water and discovered single-celled organisms, which he called "animalcules." These were the first observations of living cells.

III. The Basic Unit of Life

There are two main types of cells: โ— Prokaryotic Cells: Simpler, lack a membrane-bound nucleus and other complex organelles. Their genetic material (DNA) is

free-floating in the cytoplasm. Examples include bacteria and archaea. โ— Eukaryotic Cells: More complex, and have a membrane-bound nucleus and other specialized structures called organelles. This is the type of cell found in animals, plants, fungi, and protists. Eukaryotic cells are generally larger and more complex than prokaryotic cells.

IV. The City Within: Organelles and their Functions

Think of a cell as a tiny city. Just like a city has different buildings for different jobs, cells have organelles, which are specialized compartments that carry out specific functions: โ— Nucleus: The control center, surrounded by a nuclear membrane. It contains the cell's genetic material (DNA) which holds the instructions for building and maintaining the cell. DNA is organized into chromosomes. โ— Mitochondria: The powerhouse, generating most of the cell's energy through a process called cellular respiration. They are nicknamed the "powerhouse" because they take in glucose (sugar) and oxygen and produce ATP, the cell's main energy currency. โ— Endoplasmic Reticulum (ER): A network of membranes for transporting materials throughout the cell. There are two main types: rough ER, which has ribosomes attached to its surface for protein production, and smooth ER, which is involved in lipid (fat) synthesis, detoxification, and other functions. โ— Ribosomes: The protein factories, assemble proteins based on instructions from DNA. Ribosomes are made of RNA (ribonucleic acid) and protein and can be found free-floating in the cytoplasm or attached to the rough ER.

responding to their environment through signaling pathways, and maintaining a stable internal environment through homeostasis. โ— They can come together to form tissues, organs, and organ systems, which create the complex structure of multicellular organisms. Tissues are groups of cells that work together to perform a specific function. For example, muscle tissue is made up of muscle cells that contract to allow movement. Organs are multiple tissues working together for a more complex function. The heart, for example, is an organ made of muscle, nerve, and connective tissue that works together to pump blood throughout the body. Finally, organ systems are groups of organs that collaborate on a major life function. The circulatory system, for example, is made up of the heart, blood vessels, and blood and is responsible for transporting blood throughout the body.

VI. Cell Diversity: The Key to Life's Variety

Even though they share the basic structure, cells come in a huge variety of shapes and sizes, each specialized for a specific function. Here are some examples: โ— Muscle cells: These cells are long and thin and contain contractile proteins that allow them to contract and relax, enabling movement. There are different types of muscle cells, such as skeletal muscle cells for voluntary movement, smooth muscle cells in organs like the intestines, and cardiac muscle cells in the heart. โ— Nerve cells: These cells have long extensions called axons and dendrites that allow them to transmit electrical signals throughout the body. They are responsible for carrying messages between the brain, spinal cord, and other parts of the body. โ— Red blood cells: These cells are disc-shaped and lack a nucleus. They contain hemoglobin, a protein that binds to

oxygen, allowing them to efficiently transport oxygen from the lungs to tissues throughout the body. โ— Skin cells: These cells come in various shapes and sizes and form the outermost layer of the skin. They protect the environment and help regulate body temperature. โ— Sperm cells: These are the male reproductive cells and are motile, meaning they can move on their own. They have a flagellum (tail) for propulsion and a head containing the genetic material. โ— Egg cells: These are the female reproductive cells and are much larger than sperm cells. They contain nutrients to support the developing embryo. This diversity allows multicellular organisms to carry out complex functions and adapt to different environments. For example, the presence of muscle cells allows animals to move, while the presence of nerve cells allows them to sense their environment and respond accordingly.

VII. Conclusion

The tiny cell is truly a marvel of nature. By understanding their structure, function, and diversity, we gain a deeper appreciation for the building blocks of life and the incredible complexity of living things. Cells are the foundation of all living organisms, and their ability to work together in tissues, organs, and organ systems allows for the amazing variety of life that we see on Earth.