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Benign Prostatic Hyperplasia, Essays (university) of Medicine

Benign Prostatic Hyperplasia (BPH) is a common condition in older men. In BPH, the prostate gets bigger and slows or blocks the flow of urine. The prostate is a gland in the male reproductive system located around the urethra, the tube that carries urine from the bladder to the outside of the body. Enlargement of the prostate usually doesn't cause serious problems, but it can cause bothersome symptoms such as difficulty urinating, having to urinate frequently, and a feeling of incomplete urination. BPH is harmless and does not become cancerous, but it can affect quality of life.

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2019/2020

Available from 08/31/2023

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BENIGN PROSTATIC HYPERPLASIA
I. Introduction
Benign Prostatic Hyperplasia (BPH) is a common condition in older men. In BPH, the
prostate gets bigger and slows or blocks the flow of urine. The prostate is a gland in the male
reproductive system located around the urethra, the tube that carries urine from the bladder to the
outside of the body. Enlargement of the prostate usually doesn't cause serious problems, but it
can cause bothersome symptoms such as difficulty urinating, having to urinate frequently, and a
feeling of incomplete urination. BPH is harmless and does not become cancerous, but it can
affect quality of life.
II. DISCUSSION
IIa. Definition and Classification
Benign Prostatic Hyperplasia (BPH) is a non-malignant enlargement of the prostate, a
gland in the male reproductive system that is located around the urethra. This usually occurs in
older males and can affect the flow of urine. BPH can be classified based on its size and level of
symptoms. There are three main classifications namely:
1. Mild BPH: Prostate size less than 30 cc and mild symptoms such as increased urinary
frequency.
2. Moderate BPH: Prostate size between 30-60 cc and more serious symptoms such as
difficulty starting to urinate and a feeling of incomplete urination.
3. Severe BPH: The prostate is larger than 60 cc and the symptoms are very serious such as
urinary retention and possible infection.
This is only a guideline and a final diagnosis must be made by a doctor after conducting an
examination and assessing the level of symptoms and overall health condition.
IIb. Etiology and Risk Factors
The exact cause of BPH is not known, but several factors play a role, including:
Age: BPH usually occurs in older men and prevalence increases with age.
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BENIGN PROSTATIC HYPERPLASIA

I. Introduction Benign Prostatic Hyperplasia (BPH) is a common condition in older men. In BPH, the prostate gets bigger and slows or blocks the flow of urine. The prostate is a gland in the male reproductive system located around the urethra, the tube that carries urine from the bladder to the outside of the body. Enlargement of the prostate usually doesn't cause serious problems, but it can cause bothersome symptoms such as difficulty urinating, having to urinate frequently, and a feeling of incomplete urination. BPH is harmless and does not become cancerous, but it can affect quality of life. II. DISCUSSION IIa. Definition and Classification Benign Prostatic Hyperplasia (BPH) is a non-malignant enlargement of the prostate, a gland in the male reproductive system that is located around the urethra. This usually occurs in older males and can affect the flow of urine. BPH can be classified based on its size and level of symptoms. There are three main classifications namely:

  1. Mild BPH: Prostate size less than 30 cc and mild symptoms such as increased urinary frequency.
  2. Moderate BPH: Prostate size between 30-60 cc and more serious symptoms such as difficulty starting to urinate and a feeling of incomplete urination.
  3. Severe BPH: The prostate is larger than 60 cc and the symptoms are very serious such as urinary retention and possible infection. This is only a guideline and a final diagnosis must be made by a doctor after conducting an examination and assessing the level of symptoms and overall health condition. IIb. Etiology and Risk Factors The exact cause of BPH is not known, but several factors play a role, including:  Age: BPH usually occurs in older men and prevalence increases with age.

 Hormones: High levels of testosterone and decreased levels of estrogen can affect prostate growth.  Genetics: Genetic factors can also play a role in the formation of BPH. Factors that can increase the risk of BPH are:  Advanced age: the risk of BPH increases with age.  Family history: the risk is higher for men who have a family history of BPH.  Consumption of high-fat foods: eating foods that are high in fat can increase the risk of developing BPH.  Smoking and drinking alcohol: can increase the risk of developing BPH.  Obesity: being overweight can increase the risk of developing BPH. It should be noted that risk factors do not always lead to BPH and BPH can also occur in men without clear risk factors. Therefore, regular check-ups and consultations with doctors are important to find out health conditions and find problems early.

IId. How to Make a Diagnosis The diagnosis of BPH is enforced through several stages, including:

  1. Anamnesis (medical examination) - The doctor will conduct an interview regarding symptoms, medical and family history, and lifestyle.
  2. Physical exam - The doctor will perform a physical exam to check the prostate and make sure there are no other problems causing the symptoms.
  3. Laboratory tests - The doctor may order several laboratory tests such as urine tests and blood tests to make sure there is no infection or other health problem accompanying the symptoms.
  4. Instrumental Examination - Some of the instrumental examinations used to establish the diagnosis of BPH are:  Uroflowmetry: to measure the flow of urine.  Post-void residual volume: to measure the amount of urine remaining in the bladder after urination.  Transrectal ultrasound (TRUS): to measure the size of the prostate and confirm prostate enlargement.  Cystoscopy: to examine the inside of the urethra and bladder. The results of these steps will help your doctor determine whether your symptoms are caused by BPH or another health problem. Depending on the results, the doctor may recommend treatment or order further tests to confirm the diagnosis. IIe. Complications BPH complications include:
  5. Acute urinary retention: Occurs when the bladder cannot empty completely, leading to increased pressure and risk of infection.
  6. Urinary tract infection: Occurs due to obstructed urine flow and a bladder that does not fill regularly.
  1. Hydronephrosis: Occurs when the flow of urine is interrupted and leads to swelling of the kidneys.
  2. Kidney stones: Occur due to salt crystals that accumulate in the bladder that doesn't fill regularly.
  3. Impotence (erectile dysfunction): Occurs due to impaired blood flow and pressure on the blood vessels leading to the penis.
  4. Incontinence: Occurs when a person is unable to hold back urination.
  5. Hernia: Occurs due to excessive pressure on the abdominal wall which causes the internal organs to come out of the abdominal cavity.
  6. Death: Occurs due to severe complications such as hydronephrosis or uncontrolled infection. It is important to treat BPH symptoms in time to reduce the risk of complications and ensure a good quality of life. Treatment can help improve symptoms and prevent dangerous complications. Iif. Governance Management of BPH includes:
  7. Observation: The doctor may recommend observation for mild symptoms that do not affect the patient's quality of life.
  8. Medication Therapy: Several medications can be used to relieve BPH symptoms, such as:  Alfusozin: reduces pressure on the urethra and helps increase urine flow.  Dutasteride and finasteride: reduce prostate size.  Terazosin, doxazosin, tamsulosin: reduces pressure on the urethra.
  9. Invasive therapy: Several invasive treatments can be used to treat BPH, such as:  TURP (Transurethral resection of the prostate): cutting out part of the enlarged prostate.

III. CONCLUSION

Benign Prostatic Hyperplasia (BPH) is a condition that is common in older men and is a non-cancerous enlargement of the prostate gland. The main symptoms of BPH include difficulty starting to urinate, difficulty emptying the bladder, and frequent urination. Etiology and risk factors for BPH include age, race, and lifestyle factors. The pathophysiology of BPH involves an increase in prostate size and pressure on the urethra. Diagnosis of BPH includes physical examination, laboratory examination, and radiological examination. The management of BPH includes observation, medical therapy, invasive therapy, surgical therapy, and options depend on individual symptoms and conditions. BPH education and prevention is important to ensure a good quality of life and prevent complications. Overall, BPH is an acceptable and appropriately diagnosed condition. Proper medication and care can help manage symptoms and ensure a good quality of life for patients suffering from BPH.

BIBLIOGRAPHY

  1. Nickel JC, McVary KT. Medical therapy for lower urinary tract symptoms due to benign prostatic hyperplasia. urology. 2019; 126: 33-40.
  2. Zhang Y, Li Y, Wang Y, et al. The effectiveness and safety of alpha-blockers for benign prostatic hyperplasia: a systematic review and meta-analysis. Medicine (Baltimore). 2019; 98(17): e15330.
  3. Rha KH, Byun SS, Kim SH, et al. Transurethral resection of the prostate in benign prostatic hyperplasia: a systematic review and meta-analysis. World J Urol. 2018; 36(6): 861-870.
  4. Moysich KB, Newton KM, Mochek-Kenyon H, et al. Alcohol consumption and benign prostatic hyperplasia: a case-control study. Cancer Causes Control. 2019; 30(11): 1161-
  5. Kukreja RA, Keck BJ, Gu X, et al. Long-term outcomes of percutaneous laser ablation of the prostate for benign prostatic hyperplasia: a multicenter registry study. J Endourol. 2018; 32(9): 805-812.
  6. Chen SL, Chiang YY, Kuo HC. The effects of obesity and weight loss on benign prostatic hyperplasia: a systematic review and meta-analysis. Obesity (Silver Spring). 2018; 26(6): 986-995.
  7. Andriole GL, Kane CJ. Current management of benign prostatic hyperplasia. Nat Rev Urol. 2019; 16(8): 451-463.
  8. Hsing AW, Gao YT, McLerran DF, et al. Risk factors for benign prostatic hyperplasia: a population-based case-control study in China. Am J Epidemiol. 2019; 188(6): 1088-1095.
  9. Kim JK, Kim TH, Lee J, et al. Comparison of transurethral resection of the prostate and holmium laser enucleation of the prostate for benign prostatic hyperplasia: a systematic review and meta-analysis. Euro Urol. 2019; 76(4): 431-440.