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2025 Hematology: Blood Disorders, Diagnostics, and Therapeutics., Exams of Nursing

University of OxfordNursing

2025 Hematology: Blood Disorders, Diagnostics, and Therapeutics. 2025 Hematology: Blood Disorders, Diagnostics, and Therapeutics.

Typology: Exams

2024/2025

Available from 07/04/2025

Prof.Lorraine-Dixon
Prof.Lorraine-Dixon 🇬🇧

315 documents

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2025 Hematology: Blood Disorders, Diagnostics, and
Therapeutics.
Which cell is the origin of all blood cells?
A) Megakaryocyte
B) Lymphocyte
C) Hematopoietic stem cell ✔
D) Monocyte
2. What is the main function of erythrocytes?
A) Immune defense
B) Blood clotting
C) Oxygen transport ✔
D) Hormone transport
3. Which vitamin deficiency causes megaloblastic anemia?
A) Vitamin C
B) Vitamin B12 ✔
C) Vitamin D
D) Vitamin K
4. What is the lifespan of a normal red blood cell?
A) 21 days
B) 90 days
C) 120 days ✔
D) 365 days
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2025 Hematology: Blood Disorders, Diagnostics, and

Therapeutics.

Which cell is the origin of all blood cells?

 A) Megakaryocyte  B) Lymphocyte  C) Hematopoietic stem cell ✔  D) Monocyte

  1. What is the main function of erythrocytes?  A) Immune defense  B) Blood clotting  C) Oxygen transport ✔  D) Hormone transport
  2. Which vitamin deficiency causes megaloblastic anemia?  A) Vitamin C  B) Vitamin B12 ✔  C) Vitamin D  D) Vitamin K
  3. What is the lifespan of a normal red blood cell?  A) 21 days  B) 90 days  C) 120 days ✔  D) 365 days
  1. Which protein is responsible for oxygen transport in blood?  A) Albumin  B) Fibrinogen  C) Hemoglobin ✔  D) Myoglobin
  2. Which anemia is characterized by microcytic hypochromic red blood cells?  A) Megaloblastic anemia  B) Iron deficiency anemia ✔  C) Aplastic anemia  D) Hemolytic anemia
  3. Which test measures the intrinsic pathway of coagulation?  A) PT  B) aPTT ✔  C) Bleeding time  D) Platelet count
  4. Factor VIII deficiency causes which disorder?  A) Hemophilia B  B) Von Willebrand disease  C) Hemophilia A ✔  D) Disseminated intravascular coagulation
  5. Which is the primary site of adult hematopoiesis?

 A) Iron deficiency  B) Bone marrow failure  C) Destruction of red blood cells by autoantibodies ✔  D) Vitamin B12 deficiency

  1. Low MCV is typical of:  A) Megaloblastic anemia  B) Iron deficiency anemia ✔  C) Hemolytic anemia  D) Aplastic anemia
  2. Primary function of platelets is:  A) Oxygen transport  B) Immune response  C) Blood clotting ✔  D) Hormone secretion
  3. Common symptom of anemia is:  A) Hypertension  B) Fatigue ✔  C) Rash  D) Jaundice
  4. Pernicious anemia is caused by deficiency of:  A) Vitamin C  B) Vitamin D

 C) Vitamin B12 ✔  D) Vitamin K

  1. Increased white blood cell count is called:  A) Leukopenia  B) Leukocytosis ✔  C) Thrombocytopenia  D) Anemia
  2. Pancytopenia is a feature of:  A) Polycythemia  B) Aplastic anemia ✔  C) Leukemia  D) Hemophilia
  3. von Willebrand disease involves deficiency of:  A) Factor VIII  B) von Willebrand factor ✔  C) Fibrinogen  D) Factor IX
  4. Reed-Sternberg cells are characteristic of:  A) Non-Hodgkin lymphoma  B) Hodgkin lymphoma ✔  C) Multiple myeloma  D) Leukemia

 B) Duplication  C) Translocation between chromosomes 9 and 22 ✔  D) Inversion

  1. Multiple myeloma affects:  A) T lymphocytes  B) B lymphocytes  C) Plasma cells ✔  D) Myeloid cells
  2. Jaundice is common in:  A) Iron deficiency anemia  B) Aplastic anemia  C) Hemolytic anemia ✔  D) Megaloblastic anemia
  3. Bleeding time test evaluates:  A) Clotting factors  B) Platelet count  C) Platelet function ✔  D) Coagulation cascade
  4. Anemia of chronic disease is usually:  A) Microcytic  B) Macrocytic  C) Normocytic normochromic ✔

 D) Hemolytic

  1. Macrocytic anemia is caused by:  A) Iron deficiency  B) Vitamin B12 deficiency ✔  C) Thalassemia  D) Sideroblastic anemia
  2. Frequent infections are a symptom of:  A) Polycythemia  B) Leukemia ✔  C) Hemophilia  D) Anemia
  3. Characteristic blood smear in thalassemia shows:  A) Macrocytosis  B) Microcytosis with target cells ✔  C) Hypersegmented neutrophils  D) Spherocytes
  4. Normocytic anemia can be caused by:  A) Iron deficiency  B) Acute blood loss ✔  C) Vitamin B12 deficiency  D) Thalassemia
  5. Common cause of neutropenia is:

 C) Increased hemoglobin A  D) Decreased reticulocyte count

  1. Excessive platelet production occurs in:  A) Leukemia  B) Essential thrombocythemia ✔  C) Hemophilia  D) Aplastic anemia
  2. DIC presents with:  A) Hypertension  B) Bleeding and thrombosis ✔  C) Weight gain  D) Jaundice
  3. DIC lab findings include:  A) Increased platelets  B) Decreased platelets ✔  C) Normal PT  D) Normal fibrinogen
  4. Treatment for iron deficiency anemia is:  A) Vitamin B  B) Oral iron supplements ✔  C) Folic acid  D) Blood transfusion
  1. Folate deficiency causes:  A) Iron deficiency  B) Macrocytic anemia ✔  C) Chronic blood loss  D) Hemolysis
  2. Factor IX deficiency causes:  A) Hemophilia A  B) Hemophilia B ✔  C) Von Willebrand disease  D) Factor X deficiency
  3. Reactive thrombocytosis is caused by:  A) Infection  B) Inflammation or stress ✔  C) Aplastic anemia  D) Hemophilia
  4. CLL is characterized by:  A) Acute onset  B) Lymphocytosis with smudge cells ✔  C) Pancytopenia  D) Thrombocytopenia
  5. G6PD deficiency causes:  A) Iron deficiency

 C) EDTA ✔

 D) Sodium fluoride

  1. Which WBC is the first responder to bacterial infection?  A) Lymphocyte  B) Eosinophil  C) Neutrophil ✔  D) Basophil
  2. In pernicious anemia, which antibody is commonly present?  A) Anti-centromere  B) Anti-Ro  C) Anti-intrinsic factor antibody ✔  D) Anti-dsDNA
  3. Which condition causes hypersegmented neutrophils?  A) Iron deficiency  B) Megaloblastic anemia ✔  C) Thalassemia  D) Hemolytic anemia
  4. Which hemoglobin variant is found in sickle cell disease?  A) HbA  B) HbF  C) HbS ✔

 D) HbC

  1. Which test is used to assess iron stores in the body?  A) Serum iron  B) TIBC  C) Serum ferritin ✔  D) Reticulocyte count
  2. Which cell type is increased in chronic myeloid leukemia?  A) Lymphocytes  B) Granulocytes ✔  C) Plasma cells  D) Monocytes
  3. Which factor deficiency results in prolonged PT and normal aPTT?  A) Factor VIII  B) Factor IX  C) Factor XI  D) Factor VII ✔
  4. Which is the common cause of normocytic anemia?  A) Iron deficiency  B) Chronic disease ✔  C) Vitamin B12 deficiency  D) Thalassemia
  1. Which of the following is the most common inherited thrombophilia?  A) Protein C deficiency  B) Protein S deficiency  C) Antithrombin deficiency  D) Factor V Leiden mutation ✔
  2. Which of the following is a cause of neutrophilia?  A) Viral infections  B) Bacterial infections ✔  C) Aplastic anemia  D) Hemophilia
  3. Which of the following is a feature of acute lymphoblastic leukemia?  A) Adults over 60  B) Children and young adults ✔  C) Plasma cell proliferation  D) Chronic course
  4. Which of the following is a sign of disseminated intravascular coagulation?  A) Thrombocytosis  B) Prolonged PT and aPTT ✔  C) Increased fibrinogen  D) Polycythemia
  1. Which of the following is a cause of thrombocytopenia?  A) Polycythemia vera  B) Immune thrombocytopenic purpura ✔  C) Essential thrombocythemia  D) Leukemia
  2. Which of the following is a treatment for hemophilia A?  A) Platelet transfusion  B) Factor VIII concentrate ✔  C) Vitamin K  D) Aspirin
  3. Which of the following is a feature of polycythemia vera?  A) Anemia  B) Elevated hematocrit and hemoglobin ✔  C) Thrombocytopenia  D) Leukopenia
  4. Which of the following is a common cause of macrocytosis?  A) Iron deficiency  B) Alcoholism ✔  C) Thalassemia  D) Chronic blood loss
  5. Which of the following is a cause of microcytic anemia?  A) Vitamin B12 deficiency

 D) Hemophilia

  1. Which of the following is a cause of pancytopenia?  A) Iron deficiency  B) Aplastic anemia ✔  C) Thalassemia  D) Hemophilia
  2. Which of the following is a cause of leukocytosis?  A) Chemotherapy  B) Infection ✔  C) Aplastic anemia  D) Hemophilia
  3. Which of the following is a cause of leukopenia?  A) Infection  B) Chemotherapy ✔  C) Polycythemia vera  D) Hemophilia
  4. Which of the following is a cause of macrocytic anemia?  A) Iron deficiency  B) Hypothyroidism ✔  C) Chronic blood loss  D) Hemolytic anemia
  5. Which of the following is a cause of microcytic anemia?

 A) Vitamin B12 deficiency  B) Lead poisoning ✔  C) Aplastic anemia  D) Hemolytic anemia

  1. Which of the following is a cause of normocytic anemia?  A) Iron deficiency  B) Chronic kidney disease ✔  C) Vitamin B12 deficiency  D) Thalassemia
  2. Which of the following is a cause of thrombocytopenia?  A) Infection  B) Immune thrombocytopenic purpura ✔  C) Polycythemia vera  D) Hemophilia
  3. Which of the following is a cause of thrombocytosis?  A) Infection  B) Reactive thrombocytosis ✔  C) Aplastic anemia  D) Hemophilia
  4. Which of the following is a cause of neutrophilia?  A) Viral infections  B) Bacterial infections ✔